2 Post-Doctoral Fellow positions
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Employer: National Heart, Lung, and Blood Institute (NHLBI)
Located in: Framingham, Massachusetts
Degree Required: Masters
The Population Sciences Branch (PSB) of the National Heart, Lung, and Blood Institute (NHLBI) at the
National Institutes of Health invite applications for 2 Post-Doctoral Fellow positions in Dr. Andrew
Johnson’s Lab. Dr. Johnson is a tenured NIH Senior Investigator with stable funding, and a research lab
based at the historic Framingham Heart Study (FHS). The FHS was started in 1948 with a focus on
unlocking the risk factors behind cardiovascular disease. The Johnson Lab is highly focused on
understanding platelets and their role in both bleeding and cardiovascular disease, and how we may
improve anti-platelet therapeutics. Trainees in the Johnson Lab have gone onto successful careers in
industry and academia, and the Lab has >20,000 citations to its work with a current h-index >70.
We seek motivated, creative and bright individuals, to work at the Framingham Heart Study. The FHS,
has a wealth of genetic and OMICs data including whole genome sequence data, transcriptomes
(microarray and RNA-seq), methylome, lipidome, metabolome, microbiome and proteome. Additionally,
the Johnson Lab has led the collection of the largest global samples to date on platelet function and
platelet reactivity, both within FHS and other cohort samples. Relevant future research project areas for
Fellows include the genetics of platelet function, pharmacogenetics of anti-platelet therapy, integration of
platelet transcriptome and other OMICS data with cardiovascular risk and platelet function data, risk
prediction of cardiovascular disease based on platelet biomarkers, and the relationship between platelet
biomarkers and clinical bleeding history. Additional epidemiological questions relate to how platelets
change in aging, ethnic differences in platelet function, the influence of platelet function on cancer risk,
and the role of physical activity, dietary intake and other environmental factors on platelet function.
We collaborate widely with several Domestic and International Consortia in the area of Hematology (cell
counts), Hemostasis (clotting factors), and cardiovascular risk (MI, stroke, VTE). We are co-leading
genetic projects on platelet counts in ~1.2 million individuals in sample size to generate new target genes
controlling platelet biogenesis and decay. We partner with stem cell collaborators, zebrafish and mouse
geneticists for functional studies to follow up human platelet genetic discoveries.
Applicants must have an M.D. and/or Ph.D. and research experience in 1 or more of the following:
Epidemiology, Hematology, Platelet Biology, Statistical Genetics, Genomics, Pharmacogenomics,
and/or Bioinformatics. A proven track record of prior publications is expected.
The successful candidate will be offered a competitive salary commensurate with experience and
qualifications. The initial appointment will be for a minimum of 2 years, with appointment renewals in 1-
year increments. The post-doc must be a US citizen, resident alien, or nonresident alien who obtains a
valid employment visa.
Applicants should submit a cover letter highlighting key qualifications and research interests, and
curriculum vitae with complete bibliography to:
Andrew D. Johnson, Ph.D. at firstname.lastname@example.org
The advertisement will remain open until the positions are filled. PDF versions of documents sent by
email are strongly preferred.
HHS and NIH are Equal Opportunity Employers.
Applications from women, minorities and persons with disabilities are strongly encouraged to apply. The NHLBI/NIH is a smoke
free workplace. The NIH is dedicated to building a diverse community in its training and employment programs.
Posted on 06/25/2019
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